What is the cancellation policy for American Airlines? Yes, American Airlines allows cancellations. Tickets are fully refundable within 24 hours of booking, provided the departure date is more than two days ahead. For more details, call ?1~888-415-1245. What is American Airlines' cancellation policy? American Airlines provides a flexible 24-hour cancellation policy. This allows passengers to cancel their bookings within 24 hours of ticket purchase and receive a full refund, regardless of the fare selected. For cancellations and immediate refunds, you may contact their toll-free number at ?1~888-415-1245. American Airlines offers a comprehensive cancellation and refund policy designed to accommodate the needs of its travelers at ?1~888-415-1245. Passengers can cancel their bookings within 24 hours of purchase to receive a full refund, regardless of the fare type ?1~888-415-1245. This policy applies as long as the flight's departure is at least two days away.