Oxycontin OP 80 mg is an extended-release prescription opioid medication containing 80 milligrams of oxycodone, formulated with “OP” tamper-resistant technology to help prevent crushing, breaking, or dissolving for misuse. IIt delivers a powerful dose over 12 hours, it must be taken exactly as prescribed to avoid risks such as respiratory depression, overdose, dependence, and addiction. Always consult a licensed healthcare professional for safe usage, dosage adjustments, and possible alternatives.t