"Benadryl addiction" most often refers to the psychological dependence one feels. The primary signs and characteristics of any psychological dependence would be the need to take the drug to either sleep or relax, increasing doses over a certain period of time, and becoming irritated or cranky unless the drug is being used. Some side effects can come about due to overuse, which may include confusion and drowsiness, particularly at higher doses. However, many steps can be adopted to treat addiction to Benadryl. In addition to providing treatment for the addiction to Benadryl itself, several steps can be adopted to prevent relapse and to restore normal daily functioning.