Percocet is an FDA-approved combination pain medication that is used to soothe moderate to severe pain. It is made up of an opioid (narcotic) pain reliever (oxycodone), and a non-opioid pain reliever (acetaminophen). Oxycodone works in the brain to change how your body feels and responds to pain while acetaminophen may also reduce a fever. This prescription opioid medication should not be given to patients with known hypersensitivity to oxycodone, acetaminophen or persons who are under 18 years old. You should avoid driving, using machinery, or doing any activity that requires alertness until you can do it safely. Alcohol should also be avoided. Talk to your healthcare provider if you are using marijuana (weed) which you also can buy Percocet online.