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Oxycodone and tramadol are both commonly prescribed for pain relief, but vary significantly in their potency, addictive potential, and side effects. Oxycodone, a stronger opioid, is typically used for managing severe pain and comes with a higher risk of dependence and overdose. Tramadol, a less potent opioid, is often prescribed for moderate pain and carries a lower risk of misuse, though it can still lead to side effects like dizziness or nausea. Understanding their individual profiles helps patients and healthcare providers make informed decisions on the best treatment options for pain management.