The bacterium associated with huanglongbing in Mexico, Candidatus Liberibacter asiaticus is present in 23 citrus growing regions, where its dissemination is due to the presence of its vector, Diapohrina citri Kuwayama . In Mexico, some reports have documented differences in the severity of symptoms in infected trees according to the type of citrus ; those differences could be associated with CLas genetic variation. In order to probe this hypothesis, we analyzed a hyper variable region of the CLas genome from infected citrus leaves and D. citri adult samples from the Yucatán peninsula, and the Southeast of Mexico, as well as,growing strawberries hydroponically the coastal zone of the Pacific Ocean and Northeast Mexico. Analysis of the samples yielded at least seven electrophoretic profiles; one is widely distributed among the states of the coastal zone of the Pacific Ocean and Northeast Mexico, and the rest is in the Yucatán peninsula and the Southeast part of the country.